Nucleotides, β-glucans, ascorbic acid, α-tocoferol, and different concentrations of a vitamin-mineral premix promote growth of Nile tilapia juveniles

ABSTRACT Feed additives, such as β-glucans, nucleotides, ascorbic acid (vitamin C), and α-tocopherol E) can improve fish immunity contribute to enhanced zootechnical performance of the fish. This study aimed evaluate effect different concentrations vitamin- mineral premix with or without inclusion an immunostimulant boost (β-glucans, nucleotides vitamins C on performance, hemato-immunological parameters, histological changes, survival Nile tilapia juveniles. To this end, isocaloric isoproteic diets were prepared three vitamin-mineral (1.0, 1.5, 2.0 kg ton-1); additionally, effects 4% in diet examined considering six (without boost: 0.1%, 0.15%, 0.2%, 0.1% I, 0.15% 0.2% I). We used 24 experimental units, each including 15 juveniles (1.88 g±0.25) fed for 50 d supplemented diets. Further, indexes; changes liver, spleen, intestine; intestinal morphology; parameters evaluated. The that received supplementation showed higher values, compared those did not receive reinforcement. Weight gain (30.45g±3.06), daily weight (0.60g±0.06), final (32.41g±3.15) feed conversion (0.95±0.06) concentration 0.2%. Hematological affected by either pre-mix booster immunostimulant. There was increase number folds, length fold, total area goblet cells group Supplementation promoted growth improved morphology immunological